Lifesaving Breakthrough In Stopping Heart Attack Celebrates Milestone

This year celebrates the 30th anniversary of aprocedure that requires no general anesthesia.
medical breakthrough that has saved the lives ofSteady advances in the techniques and tools of
millions of heart attack victims and enabled heartangioplasty have made the procedure a
attack survivors to enjoy more normal lives.treatment option for more patients. In the early
It was 30 years ago that Dr. Andreas Gruentzigyears, an estimated five to 10 percent of patients
used a small tube with a tiny balloon on the end,with heart disease were candidates for
called a balloon-catheter, to open his patient'sangioplasty, and it was successful just 65 percent
blocked heart artery.of the time.
The procedure, called angioplasty, restored normalToday, approximately two-thirds of patients with
blood flow to the heart, relieved the 38-year-oldcoronary artery disease are candidates for
patient's chest pain and likely prevented a heartangioplasty, stenting and other catheter-based
attack. Before angioplasty, survivors of hearttreatments. The treatments are successful in 98
attacks often faced life-long disability and physicalpercent of patients, and major complications
restriction.occur in only 1.5 percent of cases. Just one
This year, cardiologists from around the world arepatient in 1,000 needs emergency bypass surgery.
celebrating angioplasty's 30 years of progress inRefinements in catheters and balloons have been
stopping heart attacks and treating coronarycontinuous. But dramatically improved patient
artery disease. They are also looking ahead tooutcomes are attributed to two other major
new frontiers, including the promise of angioplastyadvancements:
and stent placement to stop stroke, America's• The bare metal stent, approved by the
third-largest killer and the leading cause of seriousU.S. Food and Drug Administration in 1994, was
disability.designed to address the problem of sudden
"Thirty years ago, one in four heart attackcollapse of an artery following angioplasty. Stents
victims died," said Bonnie Weiner, M.D., presidentovercame this problem by propping the artery
of The Society for Cardiovascular Angiographyopen and restoring normal blood flow.
and Interventions (SCAI) and professor of• The drug-eluting or coated stent, first
medicine and interim chair of cardiovascularapproved in the U.S. in 2003 and designed to
medicine at St. Vincent Hospital at Worcesterrelease medication over time to interrupt the
Medical Center in Worcester, Mass. "Today, morebiologic processes that cause tissue growth and
than 95 percent survive. And it's very typical forre-narrowing inside the stent, has reduced the
heart attack survivors to return to work andincidence of tissue build-up from 40 percent in the
normal activities just a few days afterearly days to just five to seven percent today.
angioplasty."Looking ahead, angioplasty's catheter-based
"Although heart disease continues to be theprocedures and tools offer exciting potential for
number one killer in the U.S., the success andtreating other serious health issues effectively-and
progress of angioplasty is one of modernless invasively.
medicine's most inspiring stories," says StevenOne of the most exciting areas of development is
Bailey, M.D., SCAI secretary and interim chief ofthe treatment of diseased carotid arteries, the
the Division of Cardiology, professor of medicinevessels that supply blood to the brain, to stop or
at the University of Texas Health Sciencesprevent stroke.
Center at San Antonio.Catheter-based procedures are also being used to
The discovery that balloon catheters could servetreat renal arteries that supply blood to the
as tools for delivering medical therapies to arterieskidneys and arteries that provide oxygen- and
launched a new era of "interventional cardiology."nutrient-rich blood to the legs and feet.
Until then, emergency coronary artery bypassEven newer devices are being delivered via
graft surgery (CABG) and clot-busting drugs werecatheter to close a small, naturally occurring hole
the only interventions to stop heart attacks andbetween the upper left and right chambers of the
treat coronary artery disease.heart that puts some patients at a higher risk of
Angioplasty, which is frequently accompanied bystroke.
stent implantation, is a minimally invasive